Brady's reference to the fourth quarter brings back painful memories for fans of his former team, the New England Patriots.
Manning's fourth-quarter heroics in Super Bowl XLII helped the New York Giants defeat the Patriots 17-14, dashing their hopes for a perfect season.
And then Manning did it again four years later in Super Bowl XLVI, leading the Giants past the Patriots 21-17.
Rewatch Eli come alive in the fourth quarter against Brady and the Patriots in Super Bowl XLII and Super Bowl XLVI on ESPN+.