White House experts leading the national fight against the contagion have recommended wearing face coverings in public to prevent transmission of the illness.
The country posted yet another daily record of confirmed cases on Saturday night, with 66,528 new infections, while the death toll rose by almost 800 to nearly 135,000.
Hundreds of people queued to enter the park in Orlando, some sporting Mickey ears but all wearing face masks, with social distancing and other hygiene precautions also in place.