Outgoing Senate Majority Leader Mitch McConnell made his most definitive break yet with President Trump on Tuesday while the leader of the incoming Democratic majority laid out an ambitious agenda for the opening weeks of the Biden administration, signaling a dizzying changing of the guard in Washington.

“The mob was fed lies,” he said in his final floor speech closing out six years as majority leader.

Schumer (D-N.Y.) outlined a rapid-fire agenda for the coming weeks that includes confirming Biden’s Cabinet nominees, approving trillions in additional pandemic aid and barring Trump from holding office — despite an uncertain road map in the 50-50 Senate, which is struggling even to adopt its basic rules.

Schumer is set to move from minority leader to majority leader on Wednesday, when the Senate meets shortly after the inauguration of Biden and Vice President-elect Kamala D.

“The next several months will be very, very busy and a very consequential period for the United States Senate,” Schumer said on the Senate floor.

Significant obstacles threaten each of Schumer’s early goals: Republicans have thrown up early roadblocks to some of Biden’s key nominees, GOP fiscal concerns could make a bipartisan coronavirus bill difficult to pass, and Trump’s impeachment trial threatens to consume the earliest days of the Senate Democratic majority.

Beyond that, Schumer and McConnell reached an impasse Tuesday in talks to set the operating rules of the equally divided Senate — making any action a challenge — as McConnell demanded that Democrats drop any notion of ending the legislative filibuster.

But Schumer said Trump’s actions — which included repeating baseless claims of a stolen election, calling his supporters to gather in Washington on the day of the electoral vote certification, and then sending them toward the Capitol as the proceeding got underway — deserved the gravest possible reprimand under the Constitution.

“After what he has done, the consequences of which we were all witness to, Donald Trump should not be eligible to run for office ever again,” he said.

2 Democratic leader, said balancing the trial with the other pillars of the Biden agenda would depend on a “level of cooperation” with Republicans.

Looming over all of the incoming business in the Senate is the unfinished negotiation between McConnell and Schumer about precisely how a 50-50 Senate will operate.

Schumer spokesman Justin Goodman said the Democratic leader’s view is that “the fairest, most reasonable and easiest path forward is to adopt the 2001 bipartisan agreement without extraneous changes from either side.”.

Speaking on the floor Tuesday, McConnell sent a signal to Democrats by asserting that Biden enters office without “a mandate for sweeping ideological change,” given the narrow majorities in the House and Senate and Biden’s platform as a “presidential candidate who said he’d represent everyone.”.

Mayorkas, Biden’s pick for Homeland Security secretary, to the Senate floor.

Some Senate aides on Tuesday expressed hope that Janet L