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Breakthrough research shows hope for reversing damage in neurological disease - WGN TV Chicago

Breakthrough research shows hope for reversing damage in neurological disease - WGN TV Chicago

Breakthrough research shows hope for reversing damage in neurological disease - WGN TV Chicago
Oct 27, 2020 1 min, 9 secs

Scientists say they found an immune cell that can reverse damage and restore function.

Once nerve cells die, particularly in the brain and spinal cord, they don’t regenerate in adults.

“This new research has revealed a new cell type, a new type of white blood cell that actually rescues dying nerve cells and also stimulates them to grow new fibers when those fibers have been damaged,” Segal said.

It’s a white blood cell called a granulocyte, which is a general category of white blood cells that has not really been heavily implicated in repair in the past.

In multiple different compartments of the central nervous system they were able to increase nerve cell survival dramatically as well as stimulate new nerve fiber growth within mice,” he said.

They conducted a similar experiment in a petri dish that contained human nerve cells.

“We did use human nerve cells in some of our experiments and showed that the immune cell was effective in stimulating human nerve cells to grow new fibers,” Segal said.

The next step will be working out protocols to harvest immature cells from bone marrow then stimulating them to become pro-regenerative cells.

“The idea would be to harvest bone marrow cells from people with neurological disorders, treat them in a dish so they become pro-regenerative and protective and then re-introduce them as a cell therapy into those patients,” Segal said.

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