Cancer breakthrough as 'effective' treatment targets 'major cancers' without side effects - Daily Express
Nov 30, 2021 57 secs

Professor Kang said: "You can't find a drug target better than this: MTDF is important for most major human cancers, not important for normal cells, and it can be eliminated with no obvious side effects.".

Professor Kang said: "In the two papers we are publishing back-to-back today, we identify a compound, show it is effective against cancer, and show that it is very, very effective when combined with chemotherapy and immunotherapy.

Data from the National Cancer Institute in the US, indicates 99 percent of cancer patients survive within five years of receiving their diagnosis.

But only about 29 percent of patients survive if their cancer has metastasised.

Study lead author and associate researcher Minhong Shen said: "Metastatic breast cancer causes more than 40,000 deaths every year in the US, and the patients do not respond well to standard treatments, such as chemotherapies, targeted therapies and immunotherapies.

According to Professor Kang and his colleagues, MTDH allows cancer tumours to survive the stress associated with chemotherapy and "muzzles the alarm cry" of organs invaded by a tumour

"In essence, MTDH is a quintessential 'cancer fitness gene' that is uniquely required by malignant cells to survive and thrive."


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