College football picks, schedule: Predictions against the spread, odds for top 25 games in Week 14 - CBS Sports

The 2020 college football schedule was again this week hit by postponements and cancellations due to COVID-19, but the Week 14 slate is the strongest -- at least in terms of brand value -- we've had in weeks.

4 Ohio State is on the road against a Michigan State team that knocked Northwestern from the ranks of the undefeated last week, while No.

3 Clemson is going up against a tough Virginia Tech team in a road night game and No.

2 Notre Dame is the aforementioned team with a home game, but it's a massive 34-point favorite against Syracuse.

Here's the thing: Michigan State beat Northwestern last week, but it's not like it was a dominant performance.

I just don't think Michigan State has the offensive firepower to match up with the Buckeyes, and Ohio State is in desperate need of impressive wins.

If it has a chance to run up the score, it's not going to be shy about it. Pick: Ohio State (-23.5) -- Tom Fornelli.

There's a ruthlessness to the way the Tigers take care of business as the year draws closer to the College Football Playoff, and I expect that to continue Saturday night

If Virginia Tech can ugly this game up it might be able to cover, but you don't want to be betting on unusual circumstances with a Clemson team that's finding its best form late in the year (again). Pick: Clemson -22 -- Chip Patterson

Which college football picks can you make with confidence in Week 14? Visit SportsLine to see which teams will win and cover the spread -- all from a proven computer model that has returned over $3,500 in profit over the past four-plus seasons -- and find out