Common painkiller acetaminophen could alter fetal development, researchers warn - Fox News
Sep 24, 2021 1 min, 27 secs

"A new Consensus Statement summarizes human epidemiological studies and experimental research in cells and animal models, which suggest that APAP exposure during pregnancy can alter fetal development and might increase the risk of certain neurodevelopmental, reproductive and urogenital disorders.

However, Nature noted both that paracetamol is widely considered to be the safest option for relief of pain and fever in pregnancy and that the UK National Institute for Health and Care Excellence states that APAP use during pregnancy is not thought to be harmful.

The European Medicines Agency (EMA) advises that APAP can be used during pregnancy at the lowest effective dose for the shortest possible time and at the lowest possible frequency, while the U.S.

The researchers pointed out that the management of chronic pain associated with pregnancy has been understudied, arguing that a balance must be struck between "potential harm to pregnant people and/or their fetuses from untreated pain and fever and the increased risks of harm to the fetus from medications.".

"As such, the recommendations by Bauer and colleagues advise that pregnant people should only use APAP if medically indicated, that they should consult with their physician or pharmacist if they are uncertain about APAP use and that they should use the lowest effective APAP dose for the shortest possible time.

They used only studies that investigated APAP as an independent exposure, searching experimental and epidemiological literature in English available on PubMed, including systematic reviews using the search terms "acetaminophen" or "paracetamol," "endocrine," "reproduction," "urogenital," "neurodevelopment," "attention deficit disorder," "autism spectrum disorder," "hypospadias," "anogenital distance" and "cryptorchidism."

The study recommends that pregnant women should be cautioned at the beginning of pregnancy to forego APAP unless it is medically indicated, as supported by 91 scientists, clinicians and public health professionals


1. How to Get Notified When You Leave Your AirPods Pro Behind - Lifehacker
Oct 20, 2021 # technology 23 secs
2. Tony Bennett has set a new Guinness World Record - CNN
Oct 17, 2021 # entertainment 27 secs
3. Why Public Health Is in Crisis: Threats, Departures, New Laws - The New York Times
Oct 21, 2021 # health 6 mins, 13 secs
4. Toyota sets aside $3.4 billion for American electric vehicle batteries
Oct 18, 2021 # breaking 37 secs
5. New York's Orthodox neighborhoods lagging in COVID shots, records show - New York Post
Oct 21, 2021 # health 1 sec
6. COVID-19 hospitalizations in Maine spike again - Portland Press Herald - Press Herald
Oct 18, 2021 # health 0 secs
7. As Apple prepares to revamp the MacBook Pro, this coming week also marks the 30th anniversary of the original PowerBook - 9to5Mac
Oct 17, 2021 # politics 53 secs
8. After Biden says US would defend Taiwan from attack, China says there's 'no room for compromise' - Fox News
Oct 22, 2021 # politics 56 secs
9. Tuberculosis, Like Covid, Spreads in Aerosols, Scientists Report - The New York Times
Oct 19, 2021 # health 1 min, 1 sec
10. Researchers Discover First Dinosaur Era Crab Fully Preserved in 100-Million-Year-Old Amber - SciTechDaily
Oct 21, 2021 # politics 1 min, 27 secs
11. The moon takes center stage Saturday night - WTOP
Oct 16, 2021 # science 1 min, 3 secs
12. Montepulciano, addio allo storico Autogrill 'a ponte' che viene demolito
Oct 17, 2021 # breaking 20 secs
13. Lori Loughlin & Mossimo Giannulli Ask Permission to Go to Cabo Wedding - TMZ
Oct 21, 2021 # entertainment 19 secs
14. Female Crewmember Dies After Prop Gun Misfire On New Mexico Set Of Alec Baldwin Film ‘Rust’ - Deadline
Oct 22, 2021 # politics 1 min, 18 secs
15. SXSW 2022 Announces Initial Artist Lineup - Pitchfork
Oct 20, 2021 # entertainment 18 secs
16. Scientists made a wooden knife that's three times sharper than steel blades - CNET
Oct 22, 2021 # science 29 secs

SUBSCRIBE

Get monthly updates and free resources.

CONNECT WITH US

© Copyright 2021 365NEWSX - All RIGHTS RESERVED