COVID-19 antibodies appear to wane rapidly, so prepare for booster shots, study suggests - OCRegister

A single dose of either vaccine triggered antibody levels similar to what’s seen after mild COVID-19 infections.

After two doses, these folks had antibody levels approaching what’s seen after severe infections.

The first shot produced a vigorous antibody response in them, similar to what’s seen with severe natural infection — but the second shot didn’t do much of anything.

After the second vaccine, antibody levels waned in both groups comparably to natural infection, resulting in an average loss of 90% within 85 days, they found.

“We agree that many people who had a prior natural SARS-CoV-2 asymptomatic exposure or a PCR confirmed infection respond with a higher (antibody) response than people who are completely naïve,” said Dr.