COVID-19 Breakthrough: Scientists Discover How the SARS-CoV-2 Virus Evades Our Immune System - SciTechDaily
Dec 08, 2021 1 min, 43 secs
By Gracie Blackwell, Texas A&M College of Medicine.

The expression of the immune response gene ??NLRC5 (red purple) is suppressed in SARS-CoV-2 (green) infected cells.

A discovery by researchers at the Texas A&M College of Medicine could lead to new therapies to prevent the virus from proliferating in the human body.

The immune system is a complex network of cells and proteins that is designed to fight off infection and disease, especially those like the coronavirus, or SARS-CoV-2, that can cause numerous issues in the human body.

The underlying mechanism of how SARS-CoV-2 escapes from the immune system has been poorly understood.

However, researchers from the Texas A&M University College of Medicine and Hokkaido University have recently discovered a major mechanism that explains how SARS-CoV-2 can escape from the immune system and replicate in the human body.

“We found that the SARS-CoV-2 virus carries a suppressive gene that acts to inhibit a human gene in the immune system that is essential for destroying infected cells,” said Dr.

“We discovered that the reason why SARS-CoV-2 can replicate so easily is because the virus carries a suppressive gene, called ORF6, that acts to inhibit the function of NLRC5, thus inhibiting the MHC class I pathway as well.”.

Credit: Texas A&M College of Medicine.

Kobayashi and his team’s discovery shed light on the mechanism to how SARS-CoV-2 can replicate in the human body and can potentially lead to the development of new therapeutics to prevent the coronavirus from escaping the immune system and replicating in the body.

Although the introduction of COVID-19 vaccines, such as the Pfizer and Moderna vaccines, can lower an individual’s chance of contracting the virus, there is currently no permanent therapy that can entirely prevent a human from contracting SARS-CoV-2.

As this article says, Covid-19 has a suppressive gene that blocks our immune system, compromising it to no longer be able to stop the virus and other diseases from attacking organs throughout the body

December 5, 2021

December 5, 2021

December 5, 2021

December 5, 2021

December 5, 2021


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