Most children with MIS-C experienced only mild coronavirus symptoms prior to inflammatory illness: study - Fox News
Apr 07, 2021 1 min, 13 secs

Most children who developed the rare but serious multisystem inflammatory syndrome in children (MIS-C) that occurs weeks following a coronavirus infection had no or only mild symptoms of COVID-19 when they were initially infected, according to a new study that’s said to be the largest analysis of such cases in children in the U.S. .

The study authors found that the majority of the patients studied — about 75% — did not experience symptoms of COVID-19 when they had a coronavirus infection.

However, when the patients later developed MIS-C, typically some two to five weeks later, fever was among the most common symptoms, the CDC analysis found. .

The CDC in the study said their findings add to existing theories that MIS-C is likely a delayed immune response to a COVID-19 infection. .

"In this cross-sectional study of a large cohort of patients with MIS-C, 2 peaks that followed COVID-19 peaks by 2 to 5 weeks were identified

"The clinical manifestations of patients with MIS-C varied by age and presence or absence of preceding COVID-19

Development of laboratory markers or diagnostic methods to distinguish MIS-C from severe COVID-19 illness and other hyperinflammatory conditions, such as Kawasaki disease, is critical for early and prompt diagnosis and treatment," the study authors concluded, in part. "As the COVID-19 pandemic spreads, causing a third peak and more sustained transmission across the United States, physicians should maintain a high index of suspicion for MIS-C to promptly diagnose and treat these patients

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