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Nasal Alzheimer's Vaccine To Start Human Trials for the First Time - Interesting Engineering

Nasal Alzheimer's Vaccine To Start Human Trials for the First Time - Interesting Engineering

Nasal Alzheimer's Vaccine To Start Human Trials for the First Time - Interesting Engineering
Nov 25, 2021 42 secs

Brigham and Women's Hospital in Boston Massachusetts will soon begin Phase I trials of a nasal vaccine designed to prevent or slow the progression of Alzheimer's disease (AD), a press release said.

This is the first occasion when a nasal vaccine is being attempted for the disease, which affects more than six million people in the U.S.

Alois Alzheimer, the disease is a brain disorder characterized by the presence of clumps (amyloid plaques) and tangled fibers (tau tangles) between nerve cells (neurons) in the brain.

The researchers are hopeful that by triggering the immune system, specifically the white blood cells from the lymph node located in the neck area, the vaccine will clear out plaques in AD patients too. .

If successful, the same mode of treatment could be used for other neurodegenerative diseases, the press release said. 

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