New Blood Test Accurately Predicts Which COVID-19 Patients Will Develop Severe Infection - SciTechDaily
Oct 16, 2020 1 min, 23 secs
October 16, 2020.

Scientists have developed, for the first time, a score that can accurately predict which patients will develop a severe form of Covid-19.

The measurement, called the Dublin-Boston score, is designed to enable clinicians to make more informed decisions when identifying patients who may benefit from therapies, such as steroids, and admission to intensive care units.

The Dublin-Boston score can now accurately predict how severe the infection will be on day seven after measuring the patient’s blood for the first four days.

Professor Gerry McElvaney (left), the study’s senior author and a consultant in Beaumont Hospital, and Professor Ger Curley (right) stand in front of the RCSI Education and Research Centre in Beaumont Hospital, Dublin.

Based on the changes in the ratio of these two molecules over time, the researchers developed a point system where each 1-point increase was associated with a 5.6 times increased odds for a more severe outcome.

“The Dublin-Boston score is easily calculated and can be applied to all hospitalised Covid-19 patients,” said RCSI Professor of Medicine Gerry McElvaney, the study’s senior author and a consultant in Beaumont Hospital.

Reference: “A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19” by Oliver J McElvaney, Brian D Hobbs, Dandi Qiao, Oisín F McElvaney, Matthew Moll, Natalie L McEvoy, Jennifer Clarke, Eoin O’Connor, Seán Walsh, Michael H Cho, Gerard F Curley and Noel G McElvaney, 8 October 2020, EBioMedicine.

The Dublin-Boston score was developed by researchers from RCSI, Harvard University, Beaumont Hospital in Dublin and the Brigham and Women’s Hospital in Boston.

October 14, 2020

October 14, 2020

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