- Aaron Rodgers, Packers, threw for 364 yards and four touchdowns to lead Green Bay to a 43-36 win at Minnesota.
- Russell Wilson, Seahawks, had four touchdown passes and completed 31 of 35 passes for 322 yards in Seattle's 38-27 victory at Atlanta.
- Lamar Jackson, Ravens, threw for 275 yards and three touchdowns, going 20 of 25 while also racking up a team-high 45 yards rushing in Baltimore's 38-6 rout of Cleveland.
- Josh Allen, Bills, finished 33 of 46 for 312 yards and three TDs in Buffalo's 27-17 win over the New York Jets, becoming the team's first Buffalo player to top 300 yards since Tyrod Taylor in December 2016.
Trubisky threw three TD passes in the fourth quarter to help Chicago come back from a 17-point deficit.
- Gardner Minshew, Jaguars, threw three touchdown passes and finished 19 of 20 for 173 yards in Jacksonville's 27-20 win over Indianapolis.
- Adrian Peterson, Lions, ran for 93 yards on 14 carries in his Detroit debut, a 27-23 loss to Chicago, just four days after signing with the team.
- Cam Newton, Patriots, rushed for 15 times for 75 yards and two touchdowns while also throwing for 155 yards in his debut as New England's quarterback in a 21-11 victory over Miami.
- Dalvin Cook, Vikings, rushed 12 times for 50 yards, two touchdowns and two 2-point conversions in Minnesota's 43-36 loss to Green Bay.
- Davante Adams, Packers, set a career high and tied a franchise record with 14 catches for 156 yards and two scores to help Green Bay defeat Minnesota 43-36.
- DeAndre Hopkins, Cardinals, had a career-high 14 catches for 151 yards in his Arizona debut and set up Kenyan Drake's 1-yard TD run with 5:03 to play in a 24-20 win over San Francisco.
Ridley had two touchdown receptions and 130 yards receiving, while Jones had 157 yards receiving and Gage finished with 114.
- Mark Andrews, Ravens, caught two touchdown passes in Baltimore's 38-6 win over Cleveland.
- Robby Anderson, Panthers, had six catches for 115 yards and a go-ahead 75-yard score in his Carolina debut, a 34-30 loss to Las Vegas.
- Adam Thielen, Vikings, finished with six receptions for 110 yards and two TDs in Minnesota's 43-36 loss to Green Bay.
- Janoris Jenkins, Saints, returned an interception thrown by Tom Brady 36 yards for a touchdown in New Orleans' 34-23 victory over Tampa Bay.
Jacksonville's James Robinson made NFL history in his pro debut, running for 62 yards - a record for undrafted rookie running backs in season openers - in the Jaguars' 27-20 win over Indianapolis.
Washington's Ralph Nelson held the previous high for yards rushing by an undrafted rookie in Week 1, gaining 44 yards against New Orleans on Sept.
Seattle's Russell Wilson has 30,056 yards passing and 4,022 yards rushing, joining Pro Football Hall of Famer Steve Young as the only players in NFL history with at least 30,000 yards passing and 4,000 yards rushing.
Atlanta outgained Seattle 506 yards to 383, with Julio Jones, Calvin Ridley and Russell Gage all collecting more than 100 yards receiving.
24, 2016, to throw for 300 yards, going 33 of 46 for 312 yards with two touchdowns, plus another one rushing in a 27-17 win over the New York Jets.
Cam Newton ran 15 times for 75 yards in New England's 21-11 win over Miami, the most yards rushing by a Patriots quarterback since Steve Grogan had 81 in 1977.
The second pick thrown by the new, 43-year-old Bucs QB - who left the New England Patriots in free agency after 20 years and six Super Bowl triumphs - was returned 36 yards for a touchdown by Janoris Jenkins.
Newton ran 15 times for 75 yards and threw for 155 yards, leading a Patriots offensive attack that did most of its damage via the rushing game in their first game since the departure of Brady to Tampa Bay as a free agent.
Matty Ice was 37 of 54 for 450 yards and two touchdowns, the second-highest yardage total of his career.
Ryan has 51,636 career passing yards, while Elway had 51,475.
Peyton Barber ran for two touchdowns and Dwayne Haskins rallied Washington from a 17-point deficit to beat the Philadelphia Eagles 27-17 Sunday in coach Ron Rivera's debut.
Heisman Trophy winner Joe Burrow ran 23 yards untouched for a touchdown - the best moment of his NFL debut - but the Los Angeles Chargers roughed him up and rallied for a 16-13 victory over Cincinnati.
A line anchored by Joey Bosa and Melvin Ingram III held the quarterback from national champion LSU to 23 of 36 passing for 192 yards with three sacks and a costly interception.
Trubisky threw three touchdown passes in the fourth quarter to help Chicago come back from a 17-point deficit
Gardner Minshew threw three touchdown passes, including a 22-yarder to Keelan Cole in the fourth quarter, and Jacksonville opened the season by stunning Indianapolis 27-20 and spoiling Philip Rivers' debut with the Colts
The second-year pro completed 19 of 20 passes for 173 yards and no turnovers
McCaffrey racked up 134 yards from scrimmage and scored two touchdowns
He deserves some national attention - and I hope you give it to him.'' - Las Vegas coach Jon Gruden on running back Josh Jacobs, who ran for 93 yards and three touchdowns in the Raiders' 34-30 win at Carolina
To me, he's obviously the best player in the world, and his arm reflects that.'' - Baltimore tight end Mark Andrews on quarterback Lamar Jackson, who threw for 275 yards and three touchdowns, including two to Andrews, in the Ravens' 38-6 rout of Cleveland
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