Obesity-Related Neurodegeneration Mimics Alzheimer’s Disease - Neuroscience News

A new study led by scientists at The Neuro (Montreal Neurological Institute-Hospital) of McGill University finds a correlation between neurodegeneration in obese people and Alzheimer’s disease (AD) patients, suggesting that losing excess weight could slow cognitive decline in aging and lower risk for AD.

Previous research has shown that obesity is linked with Alzheimer’s disease (AD)-related changes, such as cerebrovascular damage and amyloid-β accumulation.

They compared the AD patients with healthy controls, and obese with non-obese individuals, creating maps of grey matter atrophy for each group.

Credit: Filip MorysObesity is increasingly recognized as a multisystem disease affecting respiratory, gastrointestinal, and cardiovascular systems, among others.

Reports show that obesity is linked with Alzheimer’s disease (AD)-related changes, such as cerebrovascular damage or amyloid-β accumulation.

Excess weight management could lead to improved health outcomes, slow down cognitive decline in aging, and lower the risk for AD.