Patrick Dempsey acts shocked when told on Kimmel that Ellen Pompeo is leaving Grey's Anatomy - Daily Mail

Patrick Dempsey has reacted to his former cast mate Ellen Pompeo leaving Grey's Anatomy?

The 56-year-old star was asked on Jimmy Kimmel Live.

Doctor and doctor: Before his character's death in 2015, Derek Shepherd was married to Meredith Grey, played by Pompeo.

On the show, the Disenchanted star spoke about about the impact of the show that shot both him and Pompeo to fame.

McDreamy: Despite Dempsey's character Derek 'McDreamy' Shepherd being killed off and leaving the show in 2015, the star returned to the series occasionally to make guest appearances.

Despite his character being killed off and leaving the show in 2015, the star returned to the series occasionally to make guest appearances.

The handsome doctor: The star told Kimmel he's met doctors who were inspired to pursue medicine as a career after watching him on Grey's Anatomy.

Attention please: The handsome doctor revealed he 'absolutely' receives better medical care in real life.

The Loverboy actor expressed his appreciation for a whole new generation of young people continuing to binge-watch the medical drama now streaming on Netflix.

Earlier on Thursday, Pompeo officially announced her departure from the medical drama after 19 seasons

Grey's departure was set up in last week's episode when the doctor decided to move to Boston

The episode also revealed Meredith's house went up in flames, with the only salvaged item being the post-it with Meredith and Derek's vows