Revolutionary Gigapixel 3D Microscope Captures Life in Jaw-Dropping Detail - SciTechDaily

Whether recording 3D movies of the behavior of dozens of freely swimming zebrafish or the grooming activity of fruit flies at near cellular-level detail across a very wide field of view, the device is opening new possibilities to researchers the world over.

Whether recording 3D movies of the behavior of dozens of freely swimming zebrafish or the grooming activity of fruit flies at near cellular-level detail across a very wide field of view, the device is opening new possibilities to researchers the world over.

Whether recording 3D movies of the behavior of dozens of freely swimming zebrafish or the grooming activity of fruit flies at near cellular-level detail across a very wide field of view, the device is opening new possibilities to researchers the world over.

Building upon recent work completed in close collaboration with Dr. Eva Naumann’s lab at Duke, innovative software gives the microscope the ability to take 3D measurements, provide more detail at smaller scales and make smoother movies.

“We’ve long been building our own rigs with single lenses and cameras, which have worked well for our purposes, but this is on a whole other level,” said McCarroll, an independent scientist studying pharmaceutical chemistry in the UC system’s professional researcher series.

Reference: “Parallelized computational 3D video microscopy of freely moving organisms at multiple gigapixels per second” by Kevin C. Zhou, Mark Harfouche, Colin L. Cooke, Jaehee Park, Pavan C. Konda, Lucas Kreiss, Kanghyun Kim, Joakim Jönsson, Thomas Doman, Paul Reamey, Veton Saliu, Clare B. Cook, Maxwell Zheng, John P. Bechtel, Aurélien Bègue, Matthew McCarroll, Jennifer Bagwell, Gregor Horstmeyer, Michel Bagnat and Roarke Horstmeyer, 20 March 2023, Nature Photonics.