Joe Biden, played by "Saturday Night Live" cast member James Austin Johnson, knows who's really to blame for surging COVID cases, record-setting inflation and more issues facing Americans: Spider-Man.

This week's cold open of the live NBC sketch show featured Johnson's Biden dodging tough questions from reporters during a press conference.

And, according to Johnson's Biden, Spider-Man isn't just responsible for omicron?

"I mean, if that doesn't sound like a job for Spider-Man, then I don't know what is," Johnson's Biden quipped.

Johnson's Biden then launched into a theory about multiple universes — a key plot point in "Spider-Man: No Way Home." When asked about the validity of this theory, the president gave a quip that earned applause from the studio audience