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UK to pilot blood test that may detect 50 types of cancer - CNN

UK to pilot blood test that may detect 50 types of cancer - CNN

UK to pilot blood test that may detect 50 types of cancer - CNN
Nov 27, 2020 1 min, 26 secs

Grail said in a press release that according to modeling data, "adding Galleri to existing standard of care has the potential to decrease the number of cancers diagnosed at late stage by nearly half, which could reduce the total number of cancer deaths in the UK by approximately one-fifth."

Five-year relative survival for cancer in the UK is below the European average, according to charity Cancer Research UK.

Lawrence Young, professor of Molecular Oncology at the University of Warwick, said the Galleri test was one of a number of novel blood tests being developed to detect cancer at a very early stage when it is more easily treated.

"There are a number of trials evaluating this approach and a publication from the Circulating Cell-free Genome Atlas (CCGA) consortium examining the Galleri test in 6,689 participants has generated very encouraging results in more than 50 different cancers at different stages of development," he told the Science Media Centre.

However, not all cancer experts agree that the NHS should be piloting the Galleri blood test.

Paul Pharoah, professor of Cancer Epidemiology at the University of Cambridge, told the Science Media Centre he had doubts about the scientific basis for the pilot based on the limited published research available.

"The Galleri blood test is a test that might be able to detect cancer in the blood in individuals with early cancer, though the evidence that it does this effectively is weak," he said.

"The NHS should not be investing in such a test before it has been adequately evaluated in well-conducted, large-scale clinical trials."

Michelle Mitchell, Cancer Research UK's chief executive, said tests such as that developed by Grail had "great transformative potential" if they prove effective in detecting cancer earlier.

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