She faces a minimum of 10 years in prison or a maximum of life in prison and a potential fine of $10 million.
The Justice Department accused Coronel of helping her husband pull off a Houdini-like escape from a Mexican prison in 2015.
The Sinaloa cartel boss escaped from a maximum security prison in July 2015 after slipping through a hole in the shower area of his cell.
The 2015 escape was the second time Mexican authorities lost custody of Guzman.
authorities that Coronel provided a Mexican official with $2 million to oversee Guzman's transfer from one prison to another.