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However, relative to the CDC’s contemporaneously reported state-level estimates, which did not include retroactive corrections, Delphi–Facebook and Census Household Pulse overestimated CDC state-level vaccine uptake by 16 and 9 percentage points, respectively (Extended Data Fig. 1g, h) in March 2021, and by equal or larger amounts by May 2021 (Extended Data Fig. 2g, h).

Relative estimates were no better than absolute estimates in March of 2021: there is little agreement in a survey’s estimated state-level rankings with the CDC (a Kendall rank correlation of 0.31 for Delphi–Facebook in Extended Data Fig. 1i and 0.26 for Census Household Pulse in Extended Data Fig. 1j) but they improved in May of 2021 (correlations of 0.78 and 0.74, respectively, in Extended Data Fig. 2i, j).

Among 18–64-year-olds, both Delphi–Facebook and Census Household Pulse overestimate uptake, with errors increasing over time (Extended Data Fig. 6).

The ordered filament core spans residues 282–360 in the TDP-43 low-complexity domain and adopts a previously undescribed double-spiral-shaped fold, which shows no similarity to those of TDP-43 filaments formed in vitro3,4

An abundance of glycine and neutral polar residues facilitates numerous turns and restricts β-strand length, which results in an absence of β-sheet stacking that is associated with cross-β amyloid structure

An uneven distribution of residues gives rise to structurally and chemically distinct surfaces that face external densities and suggest possible ligand-binding sites

Chris Sununu directed hospitals to set up COVID-19 “surge centers” using space normally reserved for such things as outpatient care.

People who receive the Johnson & Johnson COVID-19 vaccine are at elevated risk of getting a severe autoimmune disorder that can cause paralysis, according to a new study.

They found (pdf) 21 potential cases, 11 of which were confirmed, of Guillain-Barré syndrome (GBS) in people who got the shot.

They recorded whether the participants showed an increase in "insight," which meant they either started solving the math problems significantly quicker or they explicitly said that they figured out the hidden rule.

The virus hasn’t yet spread beyond that group — a hopeful sign that public health measures have been able to contain the variant’s spread — but test results still are pending.

"The EPIC instrument on the DSCOVR spacecraft captured the eclipse's umbra, the dark, inner shadow of planet Earth," NASA officials wrote in a description.

Now, three decades later, NASA’s James Webb Space Telescope (JWST) is finally about to launch, and Dang has scored some of its first observing time — in a research area that didn’t even exist when it was being designed.

Called K2-141b, it is a world so hot that its surface is partly molten rock.

Murchie and his team’s work was published today in Nature Communications.

The so-called Apple Watch Series 8 is likely to be announced sometime in September 2022.

Head below as we round up everything we know so far.

The caveat here is that the product still has its original one-year warranty, and the device must pass inspection.

Many GTA Online players have been very vocal about their desperation for new story content, especially more single-player missions, in the years since the game’s release, which makes The Contract a bit of a big deal.

This update will also be Dr.

Dre’s first public music release since his 2015 album Compton, meaning Rockstar managed to assuage not one but two starving fanbases.

Those devices can’t fully take advantage of most of Android 12L’s large screen optimization, but we can see some of Google’s other upgrades.

One notable change is that, in Android 12L, Google is introducing a new style for its Internet toggle and other quick settings.

Assassin's Creed: Valhalla romance options list, including The Siege of Paris romances, explained