How often you can take Tylenol? Explaining the safe use of acetaminophen for pain relief - USA TODAY

Mandy Leonard, who heads up the Department of Pharmacy Drug Information Service at the Cleveland Clinic, confirms this saying that based on what we know about acetaminophen and how it interacts with the body 4-6 hours is a strong general rule to follow.

The Tylenol website instructs that 2 pills can be taken every 6 hours while symptoms last for both Extra Strength Caplets and Coated Gels.

Patients with liver disease, or who are under-weight or older in age are better off consulting their doctor, Leonard advises, as Tylenol dosing might be different for them.

Tylenol is a common over-the-counter medication, most often taken in gel or tablet form, and is used to treat pain and fever.

An excess of Acetaminophen can be hard on the liver, however, so make sure to consult a doctor if you find yourself wondering how much is too much.

You should take the non-steroidal medications (i.e. Aleve, Ibuprofen, Motrin) with food since they can cause an upset stomach otherwise.