Without any satiating, digestion-slowing nutrients like fiber, healthy fats, or protein, orange juice can cause a spike and crash in blood sugar, which may cause weight gain in the same way that soda does, according to a JAMA study.
In fact, a Nutrition & Diabetes study found that when researchers gave participants orange juice 3 times a day between meals, they found that drinking the juice increased body fat and decreased insulin sensitivity in just four weeks.It's not much, but it does show how different your body treats fruit juice than it does whole fruit as those who increased their whole fruit intake decreased weight by −0.12 lbs a year.