This is why further ways to alleviate the symptoms of depression have been sought, for example, from nutritional research.
Additionally, cross-sectional studies have observed an association between vitamin D deficiency and depressive symptoms.
However, previous meta-analyses on the effects of vitamin D supplementation on depression have been inconclusive.
In a meta-analysis, results from multiple different studies are combined and analyzed statistically.
The new meta-analysis on the association of vitamin D supplementation with depression is the largest one published so far.These studies have investigated the efficacy of vitamin D in alleviating depressive symptoms in adults by randomized placebo-controlled trials in different populations.
The results of the meta-analysis show that vitamin D supplementation is more effective than a placebo in alleviating depressive symptoms in people with depression.“These findings will encourage new, high-level clinical trials in patients with depression in order to shed more light on the possible role of vitamin D supplementation in the treatment of depression,” Mikola concludes.Reference: “The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta‐analysis of randomized controlled trials” by Tuomas Mikola, Wolfgang Marx, Melissa M.